Article
Association of BDNF and SERT gene polymorphisms with depression among Pakistani population.
Pakistan journal of pharmaceutical sciences - 1 Jan 2021
Akhter Naheed, Iqbal Mehir Un Nisa, Maqsood Aliya, Sheikh Safdar Ali, Ali Anwar, Khan Taseer Ahmed
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) and serotonin transporter (SERT) is implicated in the adverse life events which lead to depression. The variation in genetic make-up of BDNF (Val66Met) and SERT (5'-HTTLPR) are potential biomarkers in the development of neuropsychiatric disorders including depression. The purpose of this study was to investigate the correlation of functional polymorphisms of BDNF and SERT...
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