Molecular landscape of Hereditary Melanoma.

doi:10.1016/j.critrevonc.2021.103425

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Article

Molecular landscape of Hereditary Melanoma.

Critical reviews in oncology/hematology - 1 Aug 2021

Ribeiro Moura Brasil Arnaut Joyce, Dos Santos Guimarães Isabella, Evangelista Dos Santos Anna Cláudia, de Moraes Lino da Silva Flora, Machado Jorge Ricardo, de Melo Andreia Cristina

Abstract excerpt

Melanoma is considered the most lethal skin cancer and its incidence has increased during the past decades. About 10 % of cases are classified as hereditary melanoma. Genetic predisposition usually manifests itself clinically as early onset and multiple cutaneous melanomas. Several genes have been identified as involved to melanoma susceptibility, some of them still with unknown clinical relevance. Beyond...

Topics

Genetic Counseling
Genetic Predisposition to Disease
Humans
Melanoma
Neoplastic Syndromes, Hereditary
Pancreatic Neoplasms
Skin Neoplasms

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Open in PubMed

Identifiers

PMID: 34245855
DOI: 10.1016/j.critrevonc.2021.103425

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