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Article

The impact of mitochondria on cancer treatment resistance.

Cellular oncology (Dordrecht, Netherlands) - 1 Oct 2021

van der Merwe Michelle, van Niekerk Gustav, Fourie Carla, du Plessis Manisha, Engelbrecht Anna-Mart

Abstract excerpt

BACKGROUND: The ability of cancer cells to develop treatment resistance is one of the primary factors that prevent successful treatment. Although initially thought to be dysfunctional in cancer, mitochondria are significant players that mediate treatment resistance. Literature indicates that cancer cells reutilize their mitochondria to facilitate cancer progression and treatment resistance. However, the...

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Identifiers

PMID: 34244972
DOI: 10.1007/s13402-021-00623-y
PMCID: PMC12980708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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