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Targeting cancer-cell mitochondria and metabolism to improve radiotherapy response

14 Oct 2020

Abstract excerpt

Radiotherapy is a regimen that uses ionising radiation (IR) to treat cancer. Despite the availability of several therapeutic options, cancer remains difficult to treat and only a minor percentage of patients receiving radiotherapy show a complete response to the treatment due to development of resistance to IR (radioresistance). Therefore, radioresistance is a major clinical problem and is defined as an adaptive...

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PMID: 33069104
DOI: 10.1016/j.tranon.2020.100905

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