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Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony

9 Jul 2021

Abstract excerpt

Abstract Glucantime (Sb V ) is the first-line treatment against American Tegumentary Leishmaniasis. Resistance cases to this drug have been reported and related to host characteristics and parasite phenotypes. In this study, 12 Leishmania ( Viannia ) braziliensis isolates from patients that presented clinical cure (Responders—R) and relapse or therapeutic failure (Non-responders—NR) after treatment with antimony,...

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PMID: 34244581
DOI: 10.1038/s41598-021-93665-z

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