Article
Genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in Type 1 Diabetes from an admixed Brazilian population.
Scientific reports - 8 Jul 2021
Azulay Rossana Santiago de Sousa, Porto Luís Cristóvão, Silva Dayse Aparecida, Tavares Maria da Glória, Reis Roberta Maria Duailibe Ferreira, Nascimento Gilvan Cortês, Damianse Sabrina da Silva Pereira, Rocha Viviane Chaves de Carvalho, Magalhães Marcelo, Rodrigues Vandilson, Carvalho Paulo Ricardo Vilas Boas, Faria Manuel Dos Santos, Gomes Marília Brito
Abstract excerpt
This study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and...
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