Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DIMEimmune: Robust estimation of infiltrating lymphocytes in CNS tumors from DNA methylation profiles

1 Jan 2021

Abstract excerpt

The interaction of CNS tumors with infiltrating lymphocytes plays an important role in their initiation and progression and might be related to therapeutic responses. Gene expression-based methods have been successfully used to characterize the tumor microenvironment. However, methylation data are now increasingly used for molecular diagnostics and there are currently only few methods to infer information about...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Extracellular vesicles in disease
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34235002
DOI: 10.1080/2162402x.2021.1932365

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DIMEimmune: Robust estimation of infiltrating lymphocytes in CNS tumors from DNA methylation profilesPMID 34235002Read ↗

Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumorsSemantic proximity Read ↗

Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity.Semantic proximity Read ↗

Immunomethylomic approach to explore the blood neutrophil lymphocyte ratio (NLR) in glioma survivalSemantic proximity Read ↗

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cellsSemantic proximity Read ↗

Current status of DNA methylation profiling in neuro-oncology as a diagnostic support tool: A reviewSemantic proximity Read ↗

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics dataSemantic proximity Read ↗

DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gliomaSemantic proximity Read ↗

cIMPACT-NOW update 9: Recommendations on utilization of genome-wide DNA methylation profiling for central nervous system tumor diagnosticsSemantic proximity Read ↗

GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics dataSemantic proximity Read ↗

DNA methylation heterogeneity attributable to a complex tumor immune microenvironment prompts prognostic risk in glioma.Semantic proximity Read ↗

Epigenetics and immune cells in medulloblastomaSemantic proximity Read ↗

Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumoursSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.