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Article

High L-Carnitine Levels Impede Viral Control in Chronic Hepatitis B Virus Infection.

Frontiers in immunology - 1 Jan 2021

Gu Shuqin, Fu Xin, Ye Guofu, Chen Chengcong, Li Xiaoyi, Zhong Shihong, Tang Libo, Chen Haitao, Jiang Deke, Hou Jinlin, Li Yongyin

Abstract excerpt

Persistent antigen exposure during chronic hepatitis B infection leads to exhausted immune responses, thus impeding viral control. In recent years, immunometabolism opens new therapeutic possibilities for the modulation of immune responses. Herein, we investigated the immunomodulatory effect of L-carnitine (L-Cn) on immune cells in chronic HBV infection. In this study, 141 treatment-naïve patients with chronic...

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Share to Carcinoma, Hepatocellular
Share to Carnitine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carnitine O-Palmitoyltransferase

Share to CD4-Positive T-Lymphocytes

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Share to Hepatitis B, Chronic

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Source

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Identifiers

PMID: 34234772
DOI: 10.3389/fimmu.2021.649197
PMCID: PMC8255973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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