Article
Veillonellaceae family members uniquely alter the cervical metabolic microenvironment in a human three-dimensional epithelial model
6 Jul 2021
Abstract excerpt
Bacterial vaginosis (BV) is a gynecologic disorder characterized by a shift in cervicovaginal microbiota from Lactobacillus spp. dominance to a polymicrobial biofilm composed of diverse anaerobes. We utilized a well-characterized human three-dimensional cervical epithelial cell model in conjunction with untargeted metabolomics and immunoproteomics analyses to determine the immunometabolic contribution of three...
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