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Vaginal metatranscriptome meta-analysis reveals functional BV subgroups and novel colonisation strategies

21 Dec 2024

Abstract excerpt

BACKGROUND: The application of '-omics' technologies to study bacterial vaginosis (BV) has uncovered vast differences in composition and scale between the vaginal microbiomes of healthy and BV patients. Compared to amplicon sequencing and shotgun metagenomic approaches focusing on a single or few species, investigating the transcriptome of the vaginal microbiome at a system-wide level can provide insight into the...

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PMID: 39709449
DOI: 10.1186/s40168-024-01992-w

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