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Article

Sensitivity assessment of workflows detecting rare circulating cell-free DNA targets: A study design proposal.

PloS one - 1 Jan 2021

Voss Thorsten, Ullius Andrea, Schönborn Maike, Oelmüller Uwe

Abstract excerpt

The field of liquid biopsy has seen extensive growth in recent decades, making it one of the most promising areas in molecular diagnostics. Circulating cell-free DNA (ccfDNA) especially is used as an analyte in a growing number of diagnostic assays. These assays require specified preanalytical workflows delivering ccfDNA in qualities and quantities that facilitate correct and reliable results. As each step and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34228726
DOI: 10.1371/journal.pone.0253401
PMCID: PMC8260181

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