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Article

Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes.

Progress in neuro-psychopharmacology & biological psychiatry - 20 Dec 2021

Wang Kesheng, Xu Chun, Smith Amanda, Xiao Danqing, Navia R Osvaldo, Lu Yongke, Xie Changchun, Piamjariyakul Ubolrat

Abstract excerpt

BACKGROUND: The Trail Making Test (TMT) Part A (TMT-A) is a good measure of performance on cognitive processing speed. This study aimed to perform a genome-wide association study of TMT-A in Alzheimer's disease (AD). METHODS: A total of 757 individuals with TMT-A phenotypes and 620,901 single nucleotide polymorphisms (SNPs) were extracted from the Alzheimer's Disease Neuroimaging Initiative 1 (ADNI-1) cohort. AD...

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PMID: 34224794
DOI: 10.1016/j.pnpbp.2021.110393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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