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Article

Neuroticism Is Associated with Tau Pathology in Cognitively Unimpaired Individuals with Autosomal Dominant Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Baena Ana, Bocanegra Yamile, Torres Valeria, Vila-Castelar Clara, Guzmán-Vélez Edmarie, Fox-Fuller Joshua T, Gatchel Jennifer R, Sánchez Justin, Pluim Celina F, Ramirez-Gómez Liliana, Martínez Jairo, Pineda David, Lopera Francisco, Quiroz Yakeel T

Abstract excerpt

BACKGROUND: Greater neuroticism has been associated with higher risk for Alzheimer's disease (AD) dementia. However, the directionality of this association is unclear. We examined whether personality traits differ between cognitively-unimpaired carriers of autosomal-dominant AD (ADAD) and non-carriers, and are associated with in vivo AD pathology. OBJECTIVE: To determine whether personality traits differ between...

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Identifiers

PMID: 34219716
DOI: 10.3233/JAD-210185
PMCID: PMC9113533

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