Article
Evolution of tissue and developmental specificity of transcription start sites in Bos taurus indicus.
Communications biology - 1 Jul 2021
Forutan Mehrnush, Ross Elizabeth, Chamberlain Amanda J, Nguyen Loan, Mason Brett, Moore Stephen, Garner Josie B, Xiang Ruidong, Hayes Ben J
Abstract excerpt
To further the understanding of the evolution of transcriptional regulation, we profiled genome-wide transcriptional start sites (TSSs) in two sub-species, Bos taurus taurus and Bos taurus indicus, that diverged approximately 500,000 years ago. Evolutionary and developmental-stage differences in TSSs were detected across the sub-species, including translocation of dominant TSS and changes in TSS distribution. The...
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