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Article

The effect of common variants in GDF5 gene on the susceptibility to chronic postsurgical pain.

Journal of orthopaedic surgery and research - 1 Jul 2021

Yan Shaoyao, Nie Huiyong, Bu Gang, Yuan Weili, Wang Suoliang

Abstract excerpt

BACKGROUND: The growth differentiation factor 5 (GDF5) gene regulates the growth of neuronal axons and dendrites and plays a role in the inflammatory response and tissue damage. The gene may also be associated with chronic postsurgical pain. This study aimed to reveal the relationship between SNPs in the GDF5 gene and orthopedic chronic postsurgical pain in Han Chinese population based on a case-control study....

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Identifiers

PMID: 34210342
DOI: 10.1186/s13018-021-02549-5
PMCID: PMC8247225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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