Article
Deleterious Mutations in the TPO Gene Associated with Familial Thyroid Follicular Cell Carcinoma in Dutch German Longhaired Pointers.
Genes - 29 Jun 2021
Yu Yun, Bovenhuis Henk, Wu Zhou, Laport Kimberley, Groenen Martien A M, Crooijmans Richard P M A
Abstract excerpt
Familial thyroid cancer originating from follicular cells accounts for 5-15% of all the thyroid carcinoma cases in humans. Previously, we described thyroid follicular cell carcinomas in a large number of the Dutch German longhaired pointers (GLPs) with a likely autosomal recessive inheritance pattern. Here, we investigated the genetic causes of the disease using a combined approach of genome-wide association...
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