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Article

Emerin Represses STAT3 Signaling through Nuclear Membrane-Based Spatial Control.

International journal of molecular sciences - 22 Jun 2021

Lee Byongsun, Lee Seungjae, Lee Younggwang, Park Yongjin, Shim Jaekyung

Abstract excerpt

Emerin is the inner nuclear membrane protein involved in maintaining the mechanical integrity of the nuclear membrane. Mutations in EMD encoding emerin cause Emery-Dreifuss muscular dystrophy (EDMD). Evidence is accumulating that emerin regulation of specific gene expression is associated with this disease, but the exact function of emerin has not been fully elucidated. Here, we show that emerin downregulates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34206382
DOI: 10.3390/ijms22136669
PMCID: PMC8269395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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