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Article

LMO7-null mice exhibit phenotypes consistent with emery-dreifuss muscular dystrophy.

Muscle & nerve - 1 Feb 2015

Mull Aaron, Kim Gene, Holaska James M

Abstract excerpt

INTRODUCTION: Mutations in the inner nuclear envelope protein emerin cause Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by progressive skeletal muscle wasting, cardiac conduction defects, and tendon contractures. We previously showed that emerin binds directly to the transcription regulator Lmo7 and attenuates its activity to regulate the proper temporal expression of important myogenic...

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Source

Identifiers

PMID: 24825363
DOI: 10.1002/mus.24286

Genes

LMO7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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