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Gender Specific Differences in Disease Susceptibility: The Role of Epigenetics

8 Jun 2021

Abstract excerpt

Many complex traits or diseases, such as infectious and autoimmune diseases, cancer, xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the outcome of vaccination, show a differential susceptibility between males and females. In general, the female immune system responds more efficiently to pathogens. However, this can lead to over-reactive immune responses, which may explain the...

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PMID: 34200989
DOI: 10.3390/biomedicines9060652

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