Mechanisms underlying sex differences in autoimmunity

Abstract excerpt

Autoimmune diseases are a leading cause of disability worldwide. Most autoimmune diseases occur more often in women than men, with rheumatic autoimmune diseases being among those most highly expressed in women. Several key factors, identified mainly in animal models and cell culture experiments, are important in increasing autoimmune disease in females. These include sex hormones, immune genes including those...

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• Immune Cell Function and Interaction
• Systemic Lupus Erythematosus Research
• T-cell and B-cell Immunology