Article
Our Environment Shapes Us: The Importance of Environment and Sex Differences in Regulation of Autoantibody Production
8 Mar 2018
Abstract excerpt
Consequential differences exist between the male and female immune systems’ ability to respond to pathogens, environmental insults or self-antigens, and subsequent effects on immunoregulation. In general, females when compared to their male counterparts, respond to pathogenic stimuli and vaccines more robustly, with heightened production of antibodies, pro-inflammatory cytokines, and chemokines. While the precise...
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