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Intestinal permeability in type 1 diabetes: An updated comprehensive overview

25 Jun 2021

Abstract excerpt

The etiopathogenesis of the autoimmune disease type 1 diabetes (T1D) is still largely unknown, however, both genetic and environmental factors contribute to the development of the disease. A major contact surface for environmental factors is the gastrointestinal (GI) tract, where barrier defects in T1D likely cause diabetogenic antigens to enter the body tissues, contributing to beta-cell autoimmunity. Human and...

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PMID: 34182210
DOI: 10.1016/j.jaut.2021.102674

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