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Article

Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms.

Annals of the New York Academy of Sciences - 1 May 2009

Visser Jeroen, Rozing Jan, Sapone Anna, Lammers Karen, Fasano Alessio

Abstract excerpt

Autoimmune diseases are characterized by tissue damage and loss of function due to an immune response that is directed against specific organs. This review is focused on celiac disease (CD), an autoimmune enteropathy, and type 1 diabetes (T1D), a hyperglycosaemia caused by a destructive autoimmune process targeting the insulin-producing pancreatic islet cells. Even if environmental factors and genetic...

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Identifiers

PMID: 19538307
DOI: 10.1111/j.1749-6632.2009.04037.x
PMCID: PMC2886850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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