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What morphology can teach us about renal cell carcinoma clonal evolution

27 Sept 2020

Abstract excerpt

While cancer is a clonal process, cumulative evidence suggest that tumors are rather heterogenous and are composed of multiple genetically-distinct subclones that arise at different times and either persist and co-exist, expand and evolve, or are eliminated. A paradigm of tumor heterogeneity is renal cell carcinoma (RCC). By exploiting morphological traits and building upon a framework around three axes...

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PMID: 34178206
DOI: 10.52733/kcj18n3-a1

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