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Article

Whole-genome Sequencing of Follicular Thyroid Carcinomas Reveal Recurrent Mutations in MicroRNA Processing Subunit DGCR8.

The Journal of clinical endocrinology and metabolism - 21 Oct 2021

Paulsson Johan O, Rafati Nima, DiLorenzo Sebastian, Chen Yi, Haglund Felix, Zedenius Jan, Juhlin C Christofer

Abstract excerpt

BACKGROUND: The genomic and transcriptomic landscape of widely invasive follicular thyroid carcinomas (wiFTCs) and Hürthle cell carcinoma (HCC) are poorly characterized, and subsets of these tumors lack information on genetic driver events. OBJECTIVE: The aim of this study was to bridge this gap. METHODS: We performed whole-genome and RNA sequencing and subsequent bioinformatic analyses of 11 wiFTCs and 2 HCCs...

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Share to Adenocarcinoma, Follicular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34171097
DOI: 10.1210/clinem/dgab471
PMCID: PMC8530729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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