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CRISPR-Cas9-mediated seb1 disruption in Talaromyces pinophilus EMU for its enhanced cellulase production.

Enzyme and microbial technology - 1 Oct 2020

Manglekar Rupali Rahul, Geng Anli

Abstract excerpt

Filamentous fungi are working horses for industrial enzyme production. Combinatory approaches, such as random mutagenesis and rational genetic engineering, were adopted to improve their enzyme productivity. The filamentous fungus Talaromyces pinophilus EMU is a hyper cellulase-producing filamentous fungus obtained through random mutagenesis. This study further enhanced its cellulase production through the...

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PMID: 32912697
DOI: 10.1016/j.enzmictec.2020.109646

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