Article
Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing.
Proceedings of the National Academy of Sciences of the United States of America - 22 Sept 2009
Le Crom Stéphane, Schackwitz Wendy, Pennacchio Len, Magnuson Jon K, Culley David E, Collett James R, Martin Joel, Druzhinina Irina S, Mathis Hugues, Monot Frédéric, Seiboth Bernhard, Cherry Barbara, Rey Michael, Berka Randy, Kubicek Christian P, Baker Scott E, Margeot Antoine
Abstract excerpt
Trichoderma reesei (teleomorph Hypocrea jecorina) is the main industrial source of cellulases and hemicellulases harnessed for the hydrolysis of biomass to simple sugars, which can then be converted to biofuels such as ethanol and other chemicals. The highly productive strains in use today were generated by classical mutagenesis. To learn how cellulase production was improved by these techniques, we performed...
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