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Article

Carbon Catabolite Repression in Filamentous Fungi Is Regulated by Phosphorylation of the Transcription Factor CreA.

mBio - 5 Jan 2021

de Assis Leandro José, Silva Lilian Pereira, Bayram Ozgur, Dowling Paul, Kniemeyer Olaf, Krüger Thomas, Brakhage Axel A, Chen Yingying, Dong Liguo, Tan Kaeling, Wong Koon Ho, Ries Laure N A, Goldman Gustavo H

Abstract excerpt

Filamentous fungi of the genus Aspergillus are of particular interest for biotechnological applications due to their natural capacity to secrete carbohydrate-active enzymes (CAZy) that target plant biomass. The presence of easily metabolizable sugars such as glucose, whose concentrations increase during plant biomass hydrolysis, results in the repression of CAZy-encoding genes in a process known as carbon...

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Identifiers

PMID: 33402538
DOI: 10.1128/mBio.03146-20
PMCID: PMC8545104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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