Article
Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.
Immunity - 13 Jul 2021
Wang Ruoke, Zhang Qi, Ge Jiwan, Ren Wenlin, Zhang Rui, Lan Jun, Ju Bin, Su Bin, Yu Fengting, Chen Peng, Liao Huiyu, Feng Yingmei, Li Xuemei, Shi Xuanling, Zhang Zheng, Zhang Fujie, Ding Qiang, Zhang Tong, Wang Xinquan, Zhang Linqi
Abstract excerpt
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to emerge during the global pandemic and may facilitate escape from current antibody therapies and vaccine protection. Here we showed that the South African variant B.1.351 was the most resistant to current monoclonal antibodies and convalescent plasma from coronavirus disease 2019 (COVID-19)-infected individuals, followed by the...
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