Article
SARS-COV-2 Variants: Differences and Potential of Immune Evasion.
Frontiers in cellular and infection microbiology - 1 Jan 2021
Hirabara Sandro M, Serdan Tamires D A, Gorjao Renata, Masi Laureane N, Pithon-Curi Tania C, Covas Dimas T, Curi Rui, Durigon Edison L
Abstract excerpt
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing antibody recognition. Mutations in the S gene can generate variants of concern (VOCs), which improve "viral fitness" through selective or survival advantages, such as increased ACE-2 receptor affinity, infectivity, viral replication,...
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