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Article

Inflammasome activation and IL ‐1β signalling in group A Streptococcus disease

22 Jun 2021

Abstract excerpt

Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes significant morbidity and mortality worldwide. Recent clinical evidence suggests that the inflammatory marker interleukin-1β (IL-1β) plays an important role in GAS disease progression, and presents a potential target for therapeutic intervention. Interaction with GAS activates the host inflammasome pathway to stimulate production and...

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Share to Inflammasome and immune disorders
Share to Streptococcal Infections and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34155776
DOI: 10.1111/cmi.13373

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