Article

Pro-IL-18 secreted by keratinocytes detects the group A streptococcal protease SpeB

2021-08-22

Abstract excerpt

Group A Streptococcus (GAS, Streptococcus pyogenes ) is a professional human pathogen that commonly infects the skin. Keratinocytes are one of the first cells to contact GAS, and by inducing inflammation, they can initiate the earliest immune responses to pathogen invasion. Here, we characterized the proinflammatory cytokine repertoire produced by primary human keratinocytes and surrogate cell lines commonly use...

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Identifiers and source

Literature Corpus work: 4120a7a8-0853-5165-a9bb-ee452a9f0f93
DOI: 10.1101/2021.08.22.457234

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