Article
Personalized Management of Pheochromocytoma and Paraganglioma.
Endocrine reviews - 9 Mar 2022
Nölting Svenja, Bechmann Nicole, Taieb David, Beuschlein Felix, Fassnacht Martin, Kroiss Matthias, Eisenhofer Graeme, Grossman Ashley, Pacak Karel
Abstract excerpt
Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape that allows their assignment to clusters based on underlying genetic alterations. With around 30% to 35% of Caucasian patients (a lower percentage in the Chinese population) showing germline mutations in susceptibility genes, pheochromocytomas/paragangliomas have the highest rate of heritability among all tumors. A further 35% to...
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