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Testosterone ameliorates age-related brain mitochondrial dysfunction

17 Jun 2021

Abstract excerpt

Brain mitochondrial dysfunction and reduced testosterone levels are common features of aging in men. Although evidence suggests that the two phenomena are interrelated, it is unclear whether testosterone supplementation ameliorates mitochondrial dysfunction in the aging male brain. Here, we show that testosterone supplementation significantly alleviates exploratory behavioral deficits and oxidative damage in the...

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PMID: 34139672
DOI: 10.18632/aging.203153

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