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Article

Genetic variants in bone morphogenetic proteins signaling pathway might be involved in palatal rugae phenotype in humans.

Scientific reports - 16 Jun 2021

Silva-Sousa Alice Corrêa, Marañón-Vásquez Guido Artemio, Stuani Maria Bernadete Sasso, Proff Peter, Andrades Kesly Mary Ribeiro, Baratto-Filho Flares, Matsumoto Mírian Aiko Nakane, Paddenberg Eva, Küchler Erika Calvano, Kirschneck Christian

Abstract excerpt

This study investigated, if genetic variants in BMP2, BMP4 and SMAD6 are associated with variations in the palatal rugae pattern in humans. Dental casts and genomic DNA from 75 patients were evaluated. Each patient was classified as follows: total amount of rugae; bilateral symmetry in the amount, length and shape of the palatal rugae; presence of secondary or fragmentary palatal rugae; presence of unifications;...

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Identifiers

PMID: 34135450
DOI: 10.1038/s41598-021-92169-0
PMCID: PMC8209198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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