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Article

Single Nucleotide Polymorphisms in RUNX2 and BMP2 contributes to different vertical facial profile.

PloS one - 1 Jan 2024

Reis Caio Luiz Bitencourt, Matsumoto Mirian Aiko Nakane, Stuani Maria Bernadete Sasso, Romano Fábio Lourenço, Scariot Rafaela, Schroder Angela Graciela Deliga, Nelson-Filho Paulo, Kirschneck Christian, Beisel-Memmert Svenja, Küchler Erika Calvano

Abstract excerpt

The vertical facial profile is a crucial factor for facial harmony with significant implications for both aesthetic satisfaction and orthodontic treatment planning. However, the role of single nucleotide polymorphisms (SNPs) in the development of vertical facial proportions is still poorly understood. This study aimed to investigate the potential impact of some SNPs in genes associated with craniofacial bone...

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Topics

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Share to Adolescent
Share to Bone Morphogenetic Protein 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cephalometry

Share to Core Binding Factor Alpha 1 Subunit

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 38771832
DOI: 10.1371/journal.pone.0303551
PMCID: PMC11108145

Genes

BMP2
RUNX2
BMP4
SMAD6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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