Article
Genetic Variants of BMP2 and Their Association with the Risk of Non-Syndromic Tooth Agenesis.
PloS one - 1 Jan 2016
Lu Yun, Qian Yajing, Zhang Jinglu, Gong Miao, Wang Yuting, Gu Ning, Ma Lan, Xu Min, Ma Junqing, Zhang Weibing, Pan Yongchu, Wang Lin
Abstract excerpt
Non-syndromic tooth agenesis (or non-syndromic congenitally missing tooth) is one of the most common congenital defects in humans affecting the craniofacial function and appearance. Single nucleotide polymorphisms (SNPs) have been associated with an individual's susceptibility to these anomalies. The aim of the present study was therefore to investigate the roles of the potentially functional SNPs of BMP2 in the...
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