Investigation of rs531564 Polymorphism in the Primary MicroRNA-124 Gene in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: Association with Disease Susceptibility and Clinical Characteristics.

doi:10.18502/ijaai.v20i3.6336

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Article

Investigation of rs531564 Polymorphism in the Primary MicroRNA-124 Gene in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: Association with Disease Susceptibility and Clinical Characteristics.

Iranian journal of allergy, asthma, and immunology - 6 Jun 2021

Hassani Mehdi, Dehani Mohammad, Zare Rafie Maryam, Esmaeilzadeh Emran, Davar Saeideh, Pakzad Bahram, Mosallaei Meysam, Hoseini Seyyed Mohamad, Bayat Hadi, Soosanabadi Mohsen

Abstract excerpt

MicroRNA-124 (miR-124) is known as an important regulator of the immune system and inflammatory response. Studies have reported that this miRNA is dysregulated in autoimmune disorders such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). A functional analysis demonstrated that rs531564 (C>G) affects the biogenesis of primary microRNA transcript-124 (pri-miR-124) and changes the expression of...

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PMID: 34134452
DOI: 10.18502/ijaai.v20i3.6336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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