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Article

Relationship between the FTO Genotype and Early Chronic Kidney Disease in Type 2 Diabetes: The Mediating Role of Central Obesity, Hypertension, and High Albuminuria.

Lifestyle genomics - 1 Jan 2021

Marchetti Júlia, Balbino Karla P, Hermsdorff Helen Hermana M, Juvanhol Leidjaira L, Martinez José Alfredo, Steemburgo Thais

Abstract excerpt

INTRODUCTION: Single nucleotide polymorphisms (SNP) in the fat mass and obesity-associated (FTO) gene have been associated with type 2 diabetes (T2D) and its complications. The aim of the present research was to investigate which and how (directly or indirectly) clinical and metabolic variables mediate the association between fat mass and the FTO gene and early chronic kidney disease (CKD) in individuals with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34134115
DOI: 10.1159/000516118

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Relationship between the FTO Genotype and Early Chronic Kidney Disease in Type 2 Diabetes: The Mediating Role of Central Obesity, Hypertension, and High Albuminuria.PMID 34134115Read ↗

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