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Article

Effect of the <b><i>FTO</i></b> rs9930506 Polymorphism on the Main Comorbidities of the Cardiorenal Metabolic Syndrome in an Elderly Spanish Cohort

1 Jan 2014

Abstract excerpt

BACKGROUND/AIM: Fat mass and obesity-associated (FTO) gene polymorphisms have been linked to the risk of obesity and diabetes, two well-recognized risk factors for renal disease. Our aim was to determine whether a common FTO polymorphism was associated with a reduced estimated glomerular filtration rate (eGFR) independently of body mass index (BMI) and type 2 diabetes mellitus (T2DM) in a cohort of elderly...

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Share to Chronic Kidney Disease and Diabetes
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PMID: 25254029
DOI: 10.1159/000361054

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Related research

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Effect of the <b><i>FTO</i></b> rs9930506 Polymorphism on the Main Comorbidities of the Cardiorenal Metabolic Syndrome in an Elderly Spanish CohortPMID 25254029Read ↗

The FTO gene polymorphism is associated with end-stage renal disease: two large independent case-control studies in a general population.Semantic proximity Read ↗

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The Effect of Association between Fat Mass and Obesity-associated Gene Polymorphism (rs9939609) on the Body Composition of Older People: A Systematic Review.Semantic proximity Read ↗

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.Semantic proximity Read ↗

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Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.Semantic proximity Read ↗

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