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Analytical performance of the Xpert MTB/XDR® assay for tuberculosis and expanded resistance detection.

Diagnostic microbiology and infectious disease - 1 Sept 2021

Georghiou Sophia B, Penn-Nicholson Adam, de Vos Margaretha, Macé Aurélien, Syrmis Melanie W, Jacob Kevin, Mape Alyanna, Parmar Heta, Cao Yuan, Coulter Chris, Ruhwald Morten, Pandey Sushil K, Schumacher Samuel G, Denkinger Claudia M

Abstract excerpt

In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The Xpert MTB/XDR assay is a reliable, sensitive assay for tuberculosis and expanded resistance detection.

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Identifiers

PMID: 34130215
DOI: 10.1016/j.diagmicrobio.2021.115397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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