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Article

Global analysis of a cancer model with drug resistance due to Lamarckian induction and microvesicle transfer.

Journal of theoretical biology - 21 Oct 2021

Dénes Attila, Marzban Sadegh, Röst Gergely

Abstract excerpt

Development of resistance to chemotherapy in cancer patients strongly effects the outcome of the treatment. Due to chemotherapeutic agents, resistance can emerge by Darwinian evolution. Besides this, acquired drug resistance may arise via changes in gene expression. A recent discovery in cancer research uncovered a third possibility, indicating that this phenotype conversion can occur through the transfer of...

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Identifiers

PMID: 34129816
DOI: 10.1016/j.jtbi.2021.110812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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