Article
Metabolic Phenotypes, Dependencies, and Adaptation in Lung Cancer.
Cold Spring Harbor perspectives in medicine - 1 Nov 2021
DeNicola Gina M, Shackelford David B
Abstract excerpt
Lung cancer is a heterogeneous disease that is subdivided into histopathological subtypes with distinct behaviors. Each subtype is characterized by distinct features and molecular alterations that influence tumor metabolism. Alterations in tumor metabolism can be exploited by imaging modalities that use metabolite tracers for the detection and characterization of tumors. Microenvironmental factors, including...
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