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Article

The enigmatic role of TIPE2 in asthma

4 Jun 2020

Abstract excerpt

Unlike other members of the tumor necrosis factor (TNF)-α-induced protein 8 (TNFAIP8/TIPE) family that play a carcinogenic role and regulate apoptosis, TNFAIP8-like 2 (TIPE2) can not only maintain immune homeostasis but also regulate inflammation. TIPE2 mainly restrains the activation of T cell receptor (TCR) and Toll-like receptors (TLR), regulating its downstream signaling pathways, thereby regulating...

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PMID: 32493031
DOI: 10.1152/ajplung.00069.2020

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