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Article

Hematological and genetic profiles of persons with co-inherited heterozygous β-thalassemia and supernumerary α-globin genes.

European journal of haematology - 1 May 2023

Sundaresan Durga Devi, Hira Jasbir Kaur, Chhabra Sanjeev, Trehan Amita, Khadwal Alka Rani, Malhotra Pankaj, Sharma Prashant, Das Reena

Abstract excerpt

INTRODUCTION: Thalassemias are common monogenic autosomal recessive hemoglobin disorders. The usually asymptomatic heterozygotes (β-thalassemia traits, βTT) may rarely develop non-transfusion-dependent-thalassemia (NTDT) due to co-inheritance of supernumerary α-globin genes. Literature on phenotypic/genotypic features of these rare combinations is limited. MATERIALS AND METHODS: We studied the demographic,...

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PMID: 36598439
DOI: 10.1111/ejh.13923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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