Article
Frequency of beta-thalassemia or beta-hemoglobinopathy carriers simultaneously affected with alpha-thalassemia in Iran.
Clinical laboratory - 1 Jan 2014
Alizadeh Shaban, Bavarsad Mahsa Shanaki, Dorgalaleh Akbar, Khatib Zahra Kashani, Dargahi Hossein, Nassiri Nhaid, Hamid Fatemeh, Rahim Fakher, Jaseb Kaveh, Saki Najmaldin
Abstract excerpt
BACKGROUND: Beta-thalassemias are prevalent heritable single gene disorders affecting the quantity of the hemoglobin molecule. Rarely, a co-inheritance of these impairments with alpha-thalassemia and/or a hemoglobinopathy occurs and makes an important double heterozygote or homozygous state. Thus finding these cases is essential for genetic counseling. The present study aimed to identify the prevalence of...
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