Article
Generation of IBMS-iPSC-021, -022, -023 human induced pluripotent stem cells (IBMSi016-A, IBMSi017-A, and IBMSi018-A) derived from patients with the ALDH2 rs671 polymorphism.
Stem cell research - 1 Jul 2021
Tsai Ming-Heng, Chiu Yueh-Ting, Chan Darien Zhing-Herr, Wen Cheng-Hao, Syu Shih-Han, Lu Huai-En, Huang Chi-Ying F, Lin Yenn-Jiang, Chang Shih-Lin, Lo Li-Wei, Huang Ching-Ying, Hu Yu-Feng, Hsieh Patrick C H, Chen Shih-Ann
Abstract excerpt
ALDH2 gene is coded for the aldehyde dehydrogenase (ALDH), which is an enzyme involved in alcohol metabolism. Compared to normal aldehyde dehydrogenases, a homozygous point mutation on exon 12 from G to A significantly reduces its efficiency. In this study, we have reported the generation of IBMS-iPSC-021-04, IBMS-iPSC-022-01, and IBMS-iPSC-023-03 as induced pluripotent stem cell (iPSC) lines carrying the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.