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Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?

Alcoholism, clinical and experimental research - 1 Sept 2018

Prytkova Iya, Goate Alison, Hart Ronald P, Slesinger Paul A

Abstract excerpt

Alcohol use disorder (AUD) affects millions of people and costs nearly 250 billion dollars annually. Few effective FDA-approved treatments exist, and more are needed. AUDs have a strong heritability, but only a few genes have been identified with a large effect size on disease phenotype. Genomewide association studies (GWASs) have identified common variants with low effect sizes, most of which are in noncoding...

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PMID: 29897633
DOI: 10.1111/acer.13811
PMCID: PMC6120805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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