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A single-shot Lassa vaccine induces long-term immunity and protects cynomolgus monkeys against heterologous strains

9 Jun 2021

Abstract excerpt

A safe and protective Lassa virus vaccine is crucially needed in Western Africa to stem the recurrent outbreaks of Lassa virus infections in Nigeria and the emergence of Lassa virus in previously unaffected countries, such as Benin and Togo. Major challenges in developing a Lassa virus vaccine include the high diversity of circulating strains and their reemergence from 1 year to another. To address each of these...

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PMID: 34108251
DOI: 10.1126/scitranslmed.abf6348

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