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Article

Genome wide study of tardive dyskinesia in schizophrenia.

Translational psychiatry - 8 Jun 2021

Lim Keane, Lam Max, Zai Clement, Tay Jenny, Karlsson Nina, Deshpande Smita N, Thelma B K, Ozaki Norio, Inada Toshiya, Sim Kang, Chong Siow-Ann, Lencz Todd, Liu Jianjun, Lee Jimmy

Abstract excerpt

Tardive dyskinesia (TD) is a severe condition characterized by repetitive involuntary movement of orofacial regions and extremities. Patients treated with antipsychotics typically present with TD symptomatology. Here, we conducted the largest GWAS of TD to date, by meta-analyzing samples of East-Asian, European, and African American ancestry, followed by analyses of biological pathways and polygenic risk with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34103471
DOI: 10.1038/s41398-021-01471-y
PMCID: PMC8187404

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